Table 1

Sensitivity and specificity for two ASQ-3 cut-points, conventional and optimal cut-points, according to delay defined by Bayley-III

DomainConventional*Optimal†
SensitivitySpecificityLikelihood ratio (positive)Likelihood ratio (negative)SensitivitySpecificityLikelihood ratio (positive)Likelihood ratio (negative)
Cognition65% (38–86)89% (86-92)5.98 (3.8–9.4)0.40 (0.21–0.75)65% (38–86)95% (92–97)11.96 (6.94–20.6)0.37 (0.20–0.71)
Language81% (64–93)90% (86-93)8.10 (5.68–11.56)0.21 (0.1–0.43)84% (67–95)88% (84-91)6.85 (4.99–9.40)0.18 (0.08–0.40)
Fine motor57% (18–90)88% (85-91)4.91 (2.44–9.85)0.49 (0.21–1.14)71% (29–96)71% (66–76)2.47 (1.51–4.05)0.40 (0.12–1.30)
Gross motor100% (66–100)89% (86-92)9.21 (6.94–12.21)0 (0–NaN)100% (66–100)93% (90–95)13.66 (9.62–19.38)0 (0–NaN)
  • *Conventional cut-points correspond to<70 (2SD below the norm).

  • †Optimal cut-points correspond to 60 (2.7SD), 75 (1.7SD), 59 (2.7SD) and 85 (1SD), for cognitive, language, gross, and fine motor delay, respectively.

  • ASQ-3, Ages and Stages Questionnaire V.3; NaN, ‘Not a Number’ as it cannot be defined.