Sensitivity and specificity for two ASQ-3 cut-points, conventional and optimal cut-points, according to delay defined by Bayley-III
Domain | Conventional* | Optimal† | ||||||
Sensitivity | Specificity | Likelihood ratio (positive) | Likelihood ratio (negative) | Sensitivity | Specificity | Likelihood ratio (positive) | Likelihood ratio (negative) | |
Cognition | 65% (38–86) | 89% (86-92) | 5.98 (3.8–9.4) | 0.40 (0.21–0.75) | 65% (38–86) | 95% (92–97) | 11.96 (6.94–20.6) | 0.37 (0.20–0.71) |
Language | 81% (64–93) | 90% (86-93) | 8.10 (5.68–11.56) | 0.21 (0.1–0.43) | 84% (67–95) | 88% (84-91) | 6.85 (4.99–9.40) | 0.18 (0.08–0.40) |
Fine motor | 57% (18–90) | 88% (85-91) | 4.91 (2.44–9.85) | 0.49 (0.21–1.14) | 71% (29–96) | 71% (66–76) | 2.47 (1.51–4.05) | 0.40 (0.12–1.30) |
Gross motor | 100% (66–100) | 89% (86-92) | 9.21 (6.94–12.21) | 0 (0–NaN) | 100% (66–100) | 93% (90–95) | 13.66 (9.62–19.38) | 0 (0–NaN) |
*Conventional cut-points correspond to<70 (2SD below the norm).
†Optimal cut-points correspond to 60 (2.7SD), 75 (1.7SD), 59 (2.7SD) and 85 (1SD), for cognitive, language, gross, and fine motor delay, respectively.
ASQ-3, Ages and Stages Questionnaire V.3; NaN, ‘Not a Number’ as it cannot be defined.