Multiple logistic regression model to determine independent factors associated with mortality among premature infants born <29 weeks
| Variable | OR, 95% CI | p Value |
|---|---|---|
| Antenatal steroids: none + <24 h vs complete and >7 days coverage | 1.874 (1.522 to 2.306) | <0.001 |
| 22–26 weeks | 1.936 (1.527 to 2.454) | <0.001 |
| 27–28 weeks | 1.632 (1.059–2.515) | 0.026 |
| Maternal age | ||
| <20 years | 1.172 (0.784 to 1.751) | 0.439 |
| ≥35 years | 0.982 (0.761 to 1.269) | 0.892 |
| Birth weight percentiles | ||
| SGA vs AGA | 2.874 (2.029 to 4.073) | <0.001 |
| LGA vs AGA | 1.127 (0.736 to 1.728) | <0.001 |
| Gestational age (weeks): | ||
| 22–26 weeks vs 27–28 weeks subgroup | 6.884 (5.395 to 8.784) | <0.001 |
| Hypertensive disease of pregnancy | 0.643 (0.447 to 0.924) | 0.017 |
| Assisted conception | 1.129 (0.829 to 1.537) | 0.442 |
| Male vs female | 1.320 (1.072 to 1.626) | 0.009 |
| Outborn vs inborn | 0.986 (0.693 to 1.403) | 0.939 |
In vitro fertilisation includes gamete intrafallopian transfer, zygote intrafallopian transfer, intracytoplasmic sperm injection, etc. Hyperovulation includes any hormone therapy used to stimulate ovulation.
Values are OR (95% CI). Infants who did not receive steroids and those with <24 h before delivery were set as referent group. Analysis was performed for whole 22–28 weeks cohort and then stratified for the two subgroups of 22–26 weeks and 27–28 weeks gestational age.
AGA, appropriate for gestational age; LGA, large for gestational age (>90th percentile); SGA, small for gestational age (<10th percentile).